To people in the United States passionate about improving patient outcomes, AACT is the grassroots movement raising awareness for regenerative medicine.
Are there ethical issues concerning cellular therapies?
Adult stem cells are not part of the stem cell controversy because they are not embryonic stem cells. The Catholic Church and many Protestant Denominations have issued statements encouraging the medical use of adult stem cells as an alternative to embryonic research and therapies.
What are Cellular Therapies?
Cellular therapy (CT) is the transplantation of human cells to replace or repair damaged tissue and/or cells for the purpose of enhancing the body’s own repair process to heal disease and restore tissue integrity. All tissues in the body contain cells that control infection, inflammation, autoimmune processes and facilitate tissue repair. Stem cells from the body’s bone marrow or fat (adipose) may be placed at the site of injury or disease as a way to optimize the body’s ability to heal itself through its own cells. When the human body is injured, the adult stem cells “wake up”, move through the body to the site of injury and give signals to the surrounding environment to initiate the healing process. However, as humans age, stem cells decrease in number. Therefore, cellular therapies are a method by which stem cells are harvested from an abundant source (found in bone marrow or in fat) and re-implanted at the site of injury where they are in short supply. Ethically acceptable, these simple cellular therapies are safe, cost effective approaches that may be readily utilized to gain the desired therapeutic effect. The following are a few sample indications which may be addressed through cellular therapies: • Osteoarthritis • Tendonitis • Non-healing bone fractures • Psoriasis • Alopecia • Non-healing ulcers • Stress incontinence
Stem Cells Treat Difficult Diseases
Stem Cells may be used to address joint pain to either replace surgery or to delay surgical procedures that may be necessary. Ask your physician about using stem cells for osteoarthritis or joint pain.
Auto Immune Diseases
Scientific research has shown some benefit for a variety of auto immune diseases, especially when using umbilical cord derived tissue. This tissue is called allogeneic because it does not come from your body.This therapy has shown to modulate the immune system from damaging responses while allowing the immune system to continue to fight disease.
Regenerative medicine harnesses the body’s inherent ability to heal itself by taking stem cells from a place in the body where they are more concentrated and placing them at the site of injury to induce healing.
What is Regenerative Medicine?
Regenerative medicine has been defined as the “process of replacing, engineering or regenerating human cells, tissues or organs to estore or establish normal function”. The regenerative medicine field works to harness the body’s inherent healing attributes by removing stem cells and other regenerative properties from one part of the body and placing them at the local site of disease or injury for the purpose of stimulating the body’s repair mechanism.
How do stem cells work?
Current stem cell therapies are based upon the concept that the body has a natural, inherent method of healing itself. Scientists have learned that stem cells migrate to areas of inflammation. It is known that injury and disease causes inflammation. For example, when a child skins his knee from a fall, it gets inflamed from the injury. Stem cells relay signals to the surrounding tissue to start the healing process.
Stem cells and other regenerative properties may be harvested from a more potent source in your body such as from bone marrow or from fat and placed in the place of injury or site of disease. In this manner, the stem cells signal the surrounding tissue to repair and replace cells.
AACT patient members get access to resources including:
- Clinical trial information and statistics
- Regulatory information and advocacy
- Patient Forums